The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Bronchospasm - Wheezing - Asthma
Publications
Gouel-Chéron A, Neukirch C, Aubier B, Montravers P, Nicaise P, Chollet-Martin S, Mertes PM, Aubier M, Longrois D
Anaphylactic bronchospasm during general anesthesia is not related to asthma.
Allergy. 2015;70(4):453-6
Mivacurium and bronchospasm.
Anesthesia and analgesia. 2003;97(2):484-485
Rapacuronium and the risk of bronchospasm in pediatric patients.
Anesthesia and analgesia. 2002;94(3):488-93; table of contents
Severe bronchospasm and desaturation in a child associated with rapacuronium.
Anesthesiology. 2001;94(5):923-4