The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIX.d

Lupus - Lupus syndrome (see also Vd)

Publications

Rakotoson JL, Randriamanana D, Rakotomizao JR, Andrianasolo R, Rakotoarivelo R, Andrianarisoa AC

[Severe systemic lupus erythematosus induced by isoniazide].

Revue de pneumologie clinique 2009 Dec;65;361-4 — 2009 Dec — 361-4

Hothersall TE, Mowat AG, Duthie JJ, Alexander WR

Drug-induced lupus syndrome. A case report implicating isoniazid.

Scottish medical journal 1967 Jul;13;245-7 — 1967 Jul — 245-7