The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

V.a

Angioedema (may cause UAO, asphyxia and death)

Publications

Schmutz JL, Barbaud A, Trechot P

[Urticaria and angiodema due to itraconazole].

Annales de dermatologie et de venereologie 2005 Apr;132;403 — 2005 Apr — 403

Martínez-Alonso JC, Domínguez-Ortega FJ, Fuentes-Gonzalo MJ

Urticaria and angioedema due to itraconazole.

Allergy 2003 Dec;58;1317-8 — 2003 Dec — 1317-8