The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Anaphylaxis-Anaphylactoid reaction (can be fatal)
Publications
A patient developing anaphylaxis and sensitivity to two different GnRH analogues and a review of literature.
Journal of pediatric endocrinology & metabolism : JPEM 2015 Jul;28;923-5 — 2015 Jul — 923-5
Recurrent anaphylaxis associated with gonadotropin-releasing hormone analogs: case report and review of the literature.
Pharmacotherapy 2006 Dec;26;1811-5 — 2006 Dec — 1811-5
Recurrent anaphylaxis to a depot form of GnRH analogue.
Obstetrics and gynecology 1991 Nov;78;943-6 — 1991 Nov — 943-6