The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XII.c

Pericardial effusion (w/wo tamponade)

Publications

Ueda K, Nagai S, Miyashita SI, Kaise T, Ichikawa M, Kumano K, Hangaishi A, Nannya Y, Kurokawa M

Arsenic-induced pericardial and pleural effusion without acute promyelocytic leukemia differentiation syndrome.

Leukemia research 2010 Jan;34;e25-6 — 2010 Jan — e25-6

Vizzardi E, Zanini G, Antonioli E, D'Aloia A, Raddino R, Cas LD

QT prolongation: a case of arsenical pericardial and pleural effusion.

Cardiovascular toxicology 2008 Mar;8;41-4 — 2008 Mar — 41-4

Che-Pin Lin , Huang MJ, Chang IY, Lin WY, Sheu YT

Retinoic acid syndrome induced by arsenic trioxide in treating recurrent all-trans retinoic acid resistant acute promyelocytic leukemia.

Leukemia & lymphoma 2000 Jun;38;195-8 — 2000 Jun — 195-8