The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

V.a

Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

Publications

Gupta S, Sathya B, Padhy N, Kundavi S, Thomas BE, Varma TR

Isolated bilateral pleural effusion as the sole manifestation of late onset ovarian hyperstimulation syndrome.

Journal of human reproductive sciences. 2009;2(2):83-6

Yildizhan R, Adali E, Kolusari A, Kurdoglu M, Ozgokce C, Adali F

Ovarian Hyperstimulation Syndrome with pleural effusion: a case report.

Cases journal. 2008;1(1):323

Ciepiela P, Brelik P, Baczkowski T, Kurzawa R

Isolated severe hydrothorax with respiratory distress as a main manifestation of ovarian hyperstimulation syndrome preceded by respiratory tract infection caused by Haemophilus influenzae.

Ginekologia polska. 2007;78(7):570-3

Roden S, Juvin K, Homasson JP, Israël-Biet D

An uncommon etiology of isolated pleural effusion. The ovarian hyperstimulation syndrome.

Chest. 2000;118(1):256-8

Semba S, Moriya T, Youssef EM, Sasano H

An autopsy case of ovarian hyperstimulation syndrome with massive pulmonary edema and pleural effusion.

Pathology international. 2000;50(7):549-52