The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Left or biventricular dysfunction/failure
Publications
Thiazolinediones and heart failure: the potential to precipitate irreversible cardiac dysfunction.
International journal of cardiology 2008 Jan 11;123;e35-7 — 2008 Jan 11 — e35-7
Thiazolidinedione-associated congestive heart failure and pulmonary edema.
Mayo Clinic proceedings 2003 Sep;78;1088-91 — 2003 Sep — 1088-91