The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pulmonary veno-occlusive disease
Publications
Rapidly progressive pulmonary venoocclusive disease in young women taking oral contraceptives.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2012 Sep;31;1031-6 — 2012 Sep — 1031-6
Fatal pulmonary venoocclusive disease after use of oral contraceptives.
American heart journal 1992 Dec;124;1643-4 — 1992 Dec — 1643-4