The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LI.c

Pericardial effusion (w/wo tamponade)

Publications

Lange RA, Hillis LD

Clinical practice. Acute pericarditis.

The New England journal of medicine 2004 Nov 18;351;2195-202 — 2004 Nov 18 — 2195-202

Miller DH, Haas LF

Pneumonitis, pleural effusion and pericarditis following treatment with dantrolene.

Journal of neurology, neurosurgery, and psychiatry 1984 May;47;553-4 — 1984 May — 553-4

Petusevsky ML, Faling LJ, Rocklin RE, Snider GL, Merliss AD, Moses JM, Dorman SA

Pleuropericardial reaction to treatment with dantrolene.

JAMA 1979 Dec 21;242;2772-4 — 1979 Dec 21 — 2772-4