The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Anaphylaxis-Anaphylactoid reaction (can be fatal)
Publications
Anaphylaxis to Ciprofloxacin Requiring Emergent Surgical Cricothyrotomy.
European journal of case reports in internal medicine. 2022;9(2):003180
Anaphylactoid reaction considered ciprofloxacin related: a case report and literature review.
Clinical therapeutics. 2010;32(3):515-26
Fatal anaphylaxis associated with ciprofloxacin in a patient with AIDS related complex.
BMJ (Clinical research ed.). 1989;298(6673):605