The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Anaphylaxis-Anaphylactoid reaction (can be fatal)
Publications
Adverse reactions associated with oral and parenteral use of cephalosporins: A retrospective population-based analysis.
The Journal of allergy and clinical immunology. 2015;135(3):745-52.e5
[Twenty autopsy cases of anaphylactic shock induced by cephalosporins].
Fa yi xue za zhi. 2011;27(2):125-8
Perioperative anaphylaxis in a 44-year-old man.
Allergy and asthma proceedings. 2007;28(5):602-5
Anaphylaxis: a review of 601 cases.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2006;97(1):39-43
Leone R, Conforti A, Venegoni M, Motola D, Moretti U, Meneghelli I, Cocci A, Sangiorgi Cellini G, Scotto S, Montanaro N, Velo G
Drug-induced anaphylaxis : case/non-case study based on an italian pharmacovigilance database.
Drug safety. 2005;28(6):547-56
Cephalosporin allergy.
The New England journal of medicine. 2001;345(11):804-9
[Intraoperative anaphylactic shock--report of two cases].
Ma zui xue za zhi = Anaesthesiologica Sinica. 1989;27(4):389-93