The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Angioedema (may cause UAO, asphyxia and death)
Publications
Fatal outcome of late-onset angiotensin-converting enzyme inhibitor induced angioedema: A case report.
Medicine 2018 Aug;97;e11695 — 2018 Aug — e11695
Allergic reaction related to ramipril use: a case report.
Diabetology & metabolic syndrome 2010 Jan 20;2;4 — 2010 Jan 20 — 4
Telmisartan, ramipril, or both in patients at high risk for vascular events.
The New England journal of medicine 2008 Apr 10;358;1547-59 — 2008 Apr 10 — 1547-59
Angioedema from angiotensin-converting enzyme (ACE) inhibitor treated with complement 1 (C1) inhibitor concentrate.
Acta anaesthesiologica Scandinavica 2006 Jan;50;120-2 — 2006 Jan — 120-2
Fresh frozen plasma in the treatment of resistant angiotensin-converting enzyme inhibitor angioedema.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2004 May;92;573-5 — 2004 May — 573-5
[Tongue angioedema associated with angiotensin-converting enzyme inhibitor (diagnosis, differential diagnosis, treatment)].
Medicina (Kaunas, Lithuania) 2003;39;570-3 — 2003 — 570-3
Vasopeptidase inhibition and angio-oedema.
Lancet (London, England) 2000 Aug 19;356;608-9 — 2000 Aug 19 — 608-9