The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

IV.a

Bronchospasm - Wheezing - Asthma

Publications

Popa V

Captopril-related (and -induced?) asthma.

The American review of respiratory disease 1987 Oct;136;999-1000 — 1987 Oct — 999-1000

Banaszewski M, Szajewski T, Stepi?ska J

[Captopril-induced attacks of bronchial asthma].

Kardiologia polska 1989;32;167-70 — 1989 — 167-70

Bucca C, Rolla G, Pinna G, Oliva A, Bugiani M

Hyperresponsiveness of the extrathoracic airway in patients with captopril-induced cough.

Chest 1990 Nov;98;1133-7 — 1990 Nov — 1133-7