The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Bronchospasm - Wheezing - Asthma
Publications
Acute bronchospasm associated with methylmethacrylate cement.
Anesthesiology 1998 Nov;89;1290-1 — 1998 Nov — 1290-1
Acute bronchospasm associated with polymethylmethacrylate cement.
Anesthesiology 1997 Sep;87;696-8 — 1997 Sep — 696-8
Occupational asthma due to methylmethacrylate bone cement.
British medical journal (Clinical research ed.) 1986 Jul 19;293;207 — 1986 Jul 19 — 207