The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.f

Anaphylaxis-Anaphylactoid reaction (can be fatal)

Publications

Wang DY, Forslund C, Persson U, Wiholm BE

Drug-attributed anaphylaxis.

Pharmacoepidemiology and drug safety 1998 Jul;7;269-74 — 1998 Jul — 269-74

Hernández D, de Rojas F, Martínez Escribano C, Arriaga F, Cuellar J, Molins J, Barber L

Fatal dextran-induced allergic anaphylaxis.

Allergy 2002 Sep;57;862 — 2002 Sep — 862

Perlitz Y, Oettinger M, Karam K, Lipshitz B, Simon K

Anaphylactic shock during hysteroscopy using Hyskon solution: case report and review of adverse reactions and their treatment.

Gynecologic and obstetric investigation 1996;41;67-9 — 1996 — 67-9

Chan YF, Huang ST, Chan HC, Tan PP

[Intraoperative anaphylactic shock--report of two cases].

Ma zui xue za zhi = Anaesthesiologica Sinica 1989 Dec;27;389-93 — 1989 Dec — 389-93

Ljungström KG, Revenäs B, Smedegård G, Hedin H, Richter W, Saldeen T

Histopathological lung changes in immune complex mediated anaphylactic shock in humans elicited by dextran.

Forensic science international 1988 Sep;38;251-8 — 1988 Sep — 251-8

Fanous LH, Gray A, Felmingham J

Severe anaphylactoid reactions to dextran 70.

British medical journal 1977 Nov 05;2;1189-90 — 1977 Nov 05 — 1189-90