The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

II.e

Transfusion-related acute lung injury (TRALI) (May cause ARDS)

Publications

Jones LM, Deluga N, Bhatti P, Scrape SR, Bailey JK, Coffey RA

TRALI following fresh frozen plasma resuscitation from burn shock.

Burns : journal of the International Society for Burn Injuries. 2017;43(2):397-402

Pandey S, Vyas GN

Adverse effects of plasma transfusion.

Transfusion. 2012;52 Suppl 1(Suppl 1):65S-79S

Rajan GR

Severe transfusion-related acute lung injury in the intensive care unit secondary to transfusion of fresh frozen plasma.

Anaesthesia and intensive care. 2005;33(3):400-2

van der Werff YD, van der Houwen HK, Heijmans PJ, Duurkens VA, Leusink HA, van Heesewijk HP, de Boer A

Postpneumonectomy pulmonary edema. A retrospective analysis of incidence and possible risk factors.

Chest. 1997;111(5):1278-84