The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Organizing pneumonia pattern (an area or areas of consolidation on imaging)
Publications
Piciucchi S, Romagnoli M, Chilosi M, Bigliazzi C, Dubini A, Beomonte Zobel B, Gavelli G, Carloni A, Poletti V
Prospective evaluation of drug-induced lung toxicity with high-resolution CT and transbronchial biopsy.
La Radiologia medica 2011 Mar;116;246-63 — 2011 Mar — 246-63
An unusual radiologic pattern of cryptogenic organizing pneumonia: diffuse pulmonary nodules in a leukemia patient.
Korean journal of radiology 2009 Jan-Feb;10;93-6 — 2009 Jan-Feb — 93-6
Fulminant bronchiolitis obliterans organizing pneumonia following 2 d of treatment with hydroxyurea, interferon-alpha and oral cytarabine ocfosfate for chronic myelogenous leukemia.
European journal of haematology 2004 Jul;73;67-70 — 2004 Jul — 67-70
Bronchiolitis obliterans organizing pneumonia in three children with acute leukaemias treated with cytosine arabinoside and anthracyclines.
The European respiratory journal 1997 May;10;1187-90 — 1997 May — 1187-90