The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Autoimmunity-Autoimmune conditions (+ANA, +anti-ds-DNA, +ANCAs, other auto-Abs)
Publications
Marzo-Ortega H, Baxter K, Strauss RM, Drysdale S, Griffiths B, Misbah SA, Gough A, Cunliffe WJ, Emery P
Is minocycline therapy in acne associated with antineutrophil cytoplasmic antibody positivity? A cross-sectional study.
The British journal of dermatology 2007 May;156;1005-9 — 2007 May — 1005-9
[Systemic reaction induced my minocycline treatment: a report of four patients and a review of the literature].
La Revue de medecine interne 1999 Oct;20;869-74 — 1999 Oct — 869-74
Minocycline-induced autoimmune syndromes: an overview.
Seminars in arthritis and rheumatism 1999 Jun;28;392-7 — 1999 Jun — 392-7