The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.a

Pneumonitis (interstitial lung disease/ILD)

Publications

Hernández Pérez JM, Acosta Fernández O, Castro López-Tarruella V

[Gold salt-induced lung disease].

Archivos de bronconeumologia 2004 Nov;40;540 — 2004 Nov — 540

Sinha A, Silverstone EJ, O'Sullivan MM

Gold-induced pneumonitis: computed tomography findings in a patient with rheumatoid arthritis.

Rheumatology (Oxford, England) 2001 Jun;40;712-4 — 2001 Jun — 712-4

Reinicke C

[Pulmonary side effects of gold treatment].

Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete 1981 Dec 15;36;969-72 — 1981 Dec 15 — 969-72

Levinson ML, Lynch JP, Bower JS

Reversal of progressive, life-threatening gold hypersensitivity pneumonitis by corticosteroids.

The American journal of medicine 1981 Nov;71;908-12 — 1981 Nov — 908-12

Heyd J, Simmeran A

Gold-induced lung disease.

Postgraduate medical journal 1983 Jun;59;368-70 — 1983 Jun — 368-70

Bellelli A, Boiardi L, Tumiati B, Brigati C

Diffuse interstitial lung disease associated with hypersensitivity to gold salt.

Clinical and experimental rheumatology 1985 Apr-Jun;3;181-2 — 1985 Apr-Jun — 181-2

Agarwal R, Sharma SK, Malaviya AN

Gold-induced hypersensitivity pneumonitis in a patient with rheumatoid arthritis.

Clinical and experimental rheumatology 1989 Jan-Feb;7;89-90 — 1989 Jan-Feb — 89-90

Fernández Casares M, Casas HA, Leczycki H

[Pulmonary toxicity of gold salts].

Medicina 1991;51;59-61 — 1991 — 59-61