The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Sarcoid-like granulomatosis (endo-/extrathoracic)
Publications
High Risk of Infection During Triple Therapy with First-Generation Protease Inhibitors: A Nationwide Cohort Study.
Journal of gastrointestinal and liver diseases : JGLD 2016 Jun;25;197-204 — 2016 Jun — 197-204
Diffuse Interstitial Pulmonary Infiltrates in Malignant Melanoma.
Respiratory care 2015 Jul;60;e115-7 — 2015 Jul — e115-7
Interferon-alpha-induced sarcoidosis in a patient being treated for hepatitis C.
The American journal of case reports 2014;15;235-8 — 2014 — 235-8
Cutaneous and pulmonary sarcoidosis following treatment of multiple sclerosis with interferon-?-1b: a case report.
Journal of medical case reports 2013 Dec 13;7;270 — 2013 Dec 13 — 270
Joshita S, Shirahata K, Yazaki Y, Okaniwa S, Nakamura Y, Kimura T, Noami S, Horigome R, Yagi H, Ito N, Yamazaki A, Akahane Y, Umemura T, Yoshizawa K, Tanaka E, Ota M
Cutaneous sarcoidosis in a chronic hepatitis C patient receiving pegylated interferon and ribavirin therapy.
Hepatology research : the official journal of the Japan Society of Hepatology 2013 Jul;43;801-7 — 2013 Jul — 801-7
Interferon-?-induced pulmonary sarcoidosis in a 30-year-old woman treated for multiple sclerosis: a case report.
Journal of medical case reports 2012 Oct 08;6;344 — 2012 Oct 08 — 344
Interferon-induced sarcoidosis with osseous involvement in a patient with melanoma.
Hellenic journal of nuclear medicine 2011 Jan-Apr;14;68-9 — 2011 Jan-Apr — 68-9
Development of interferon induced sarcoidosis in a patient with familial mediterranean fever.
Tuberkuloz ve toraks 2008;56;319-24 — 2008 — 319-24
Interferon-induced sarcoidosis.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 2006 Oct;12;241-8 — 2006 Oct — 241-8
Cutaneous, pulmonary and hepatic sarcoidosis associated with autoimmune complications during interferon-alpha treatment for hepatitis C virus infection.
Journal of the European Academy of Dermatology and Venereology : JEADV 2006 Apr;20;442-5 — 2006 Apr — 442-5
Sarcoidosis in patients with chronic hepatitis C virus infection: analysis of 68 cases.
Medicine 2005 Mar;84;69-80 — 2005 Mar — 69-80
Pulmonary sarcoidosis following interferon therapy for advanced renal cell carcinoma.
Cancer 1987 Mar 01;59;896-900 — 1987 Mar 01 — 896-900