The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.k

Sarcoid-like granulomatosis (endo-/extrathoracic)

Publications

Berden FA, van Zwietering IM, Maan R, de Knegt RJ, Kievit W, Drenth JP

High Risk of Infection During Triple Therapy with First-Generation Protease Inhibitors: A Nationwide Cohort Study.

Journal of gastrointestinal and liver diseases : JGLD. 2016;25(2):197-204

Bräunlich J, Seyfarth HJ, Frille A, Wirtz H

Diffuse Interstitial Pulmonary Infiltrates in Malignant Melanoma.

Respiratory care. 2015;60(7):e115-7

Trien R, Cooper CJ, Paez D, Colon E, Ajmal S, Salameh H

Interferon-alpha-induced sarcoidosis in a patient being treated for hepatitis C.

The American journal of case reports. 2014;15:235-8

Sahraian MA, Moghadasi AN, Owji M, Maboudi M, Kosari F, McGee JC, Minagar A

Cutaneous and pulmonary sarcoidosis following treatment of multiple sclerosis with interferon-β-1b: a case report.

Journal of medical case reports. 2013;7:270

Joshita S, Shirahata K, Yazaki Y, Okaniwa S, Nakamura Y, Kimura T, Noami S, Horigome R, Yagi H, Ito N, Yamazaki A, Akahane Y, Umemura T, Yoshizawa K, Tanaka E, Ota M

Cutaneous sarcoidosis in a chronic hepatitis C patient receiving pegylated interferon and ribavirin therapy.

Hepatology research : the official journal of the Japan Society of Hepatology. 2013;43(7):801-7

Petousi N, Thomas EC

Interferon-β-induced pulmonary sarcoidosis in a 30-year-old woman treated for multiple sclerosis: a case report.

Journal of medical case reports. 2012;6:344

Meristoudis G, Tsaroucha A, Ilias I, Giannakopoulos V, Batsakis C, Christakopoulou J

Interferon-induced sarcoidosis with osseous involvement in a patient with melanoma.

Hellenic journal of nuclear medicine. 2011;14(1):68-9

Oz GS, Emri S, Apras Bilgen S

Development of interferon induced sarcoidosis in a patient with familial mediterranean fever.

Tuberkuloz ve toraks. 2008;56(3):319-24

Doyle MK, Berggren R, Magnus JH

Interferon-induced sarcoidosis.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases. 2006;12(5):241-8

Akay BN, Ekmekci P, Sanli H, Celik G, Bozdayi M

Cutaneous, pulmonary and hepatic sarcoidosis associated with autoimmune complications during interferon-alpha treatment for hepatitis C virus infection.

Journal of the European Academy of Dermatology and Venereology : JEADV. 2006;20(4):442-5

Ramos-Casals M, Mañá J, Nardi N, Brito-Zerón P, Xaubet A, Sánchez-Tapias JM, Cervera R, Font J, HISPAMEC Study Group

Sarcoidosis in patients with chronic hepatitis C virus infection: analysis of 68 cases.

Medicine. 2005;84(2):69-80

Abdi EA, Nguyen GK, Ludwig RN, Dickout WJ

Pulmonary sarcoidosis following interferon therapy for advanced renal cell carcinoma.

Cancer. 1987;59(5):896-900