The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIII.f

Bronchospasm and angioedema

Publications

Liccardi G, Bilò M, Mauro C, Salzillo A, Piccolo A, D'Amato M, Liccardi A, D'Amato G

Oxytocin: an unexpected risk for cardiologic and broncho-obstructive effects, and allergic reactions in susceptible delivering women.

Multidisciplinary respiratory medicine 2013 Oct 20;8;67 — 2013 Oct 20 — 67

Cabestrero D, Pérez-Paredes C, Fernández-Cid R, Arribas MA

Bronchospasm and laryngeal stridor as an adverse effect of oxytocin treatment.

Critical care (London, England) 2003 Oct;7;392 — 2003 Oct — 392