The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
The immune reconstitution syndrome (IRCS)
Publications
Large liquefaction of lymph nodes during tuberculosis-associated immune reconstitution inflammatory syndrome in an HIV-infected woman.
BMJ case reports 2012 Sep 24;2012; — 2012 Sep 24
Acute microbiologically negative hypoxic interstitial pneumonia on HAART: Immune Reconstitution Inflammatory Syndrome unmasking Pneumocystis jiroveci infection with an atypical presentation.
Journal of medicine and life 2012 Jun 12;5;189-91 — 2012 Jun 12 — 189-91
Pulmonary manifestations of the immune reconstitution inflammatory syndrome.
Current opinion in pulmonary medicine 2011 May;17;180-8 — 2011 May — 180-8
Reconstitution of immune responses to tuberculosis in patients with HIV infection who receive antiretroviral therapy.
Chest 2002 Aug;122;597-602 — 2002 Aug — 597-602
Shelburne SA, Hamill RJ, Rodriguez-Barradas MC, Greenberg SB, Atmar RL, Musher DW, Gathe JC, Visnegarwala F, Trautner BW
Immune reconstitution inflammatory syndrome: emergence of a unique syndrome during highly active antiretroviral therapy.
Medicine 2002 May;81;213-27 — 2002 May — 213-27