The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Anaphylaxis-Anaphylactoid reaction (can be fatal)
Publications
Images in clinical medicine. Anaphylaxis associated with blue dye.
The New England journal of medicine. 2012;367(21):2026
Anaphylaxis to patent blue V: a case series and proposed diagnostic protocol.
Allergy. 2010;65(3):396-400
Biphasic anaphylactic reaction to blue dye during sentinel lymph node biopsy.
World journal of surgical oncology. 2008;6:79
Near-fatal anaphylaxis to patent blue V.
The British journal of dermatology. 2004;150(5):1037-8
Toxicity of Food Drug and Cosmetic Blue No. 1 dye in critically ill patients.
Chest. 2004;125(2):793-5
Anaphylactic reaction to methylene blue dye after laparoscopic chromopertubation.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics. 2003;81(1):71-2
Anaphylactic/anaphylactoid reaction to contrast dye administered in the ureter.
Journal of clinical anesthesia. 1993;5(6):510-2
Hazards of intravenous indigo carmine, fluorescein, and methylene blue.
Texas medicine. 1980;76(10):49-51