The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIX.f

Anaphylaxis-Anaphylactoid reaction (can be fatal)

Publications

Pouessel G, Tacquard C, Tanno LK, Mertes PM, Lezmi G

Anaphylaxis mortality in the perioperative setting: Epidemiology, elicitors, risk factors and knowledge gaps.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2024 Jan;54;11-20 — 2024 Jan — 11-20

Dhopeshwarkar N, Sheikh A, Doan R, Topaz M, Bates DW, Blumenthal KG, Zhou L

Drug-Induced Anaphylaxis Documented in Electronic Health Records.

The journal of allergy and clinical immunology. In practice 2019 Jan;7;103-111 — 2019 Jan — 103-111

Koplin JJ, Martin PE, Allen KJ

An update on epidemiology of anaphylaxis in children and adults.

Current opinion in allergy and clinical immunology 2011 Oct;11;492-6 — 2011 Oct — 492-6

Gruchalla RS, Pirmohamed M

Clinical practice. Antibiotic allergy.

The New England journal of medicine 2006 Feb 09;354;601-9 — 2006 Feb 09 — 601-9

Leone R, Conforti A, Venegoni M, Motola D, Moretti U, Meneghelli I, Cocci A, Sangiorgi Cellini G, Scotto S, Montanaro N, Velo G

Drug-induced anaphylaxis : case/non-case study based on an italian pharmacovigilance database.

Drug safety 2005;28;547-56 — 2005 — 547-56

MINOZZI A

[On the pathogenesis of hemorrhagic phenomena during anaphylactic shock from penicillin].

Minerva medica 1959 Oct 31;50;3482-9 — 1959 Oct 31 — 3482-9

JAMES LP, AUSTEN KF

FATAL SYSTEMIC ANAPHYLAXIS IN MAN.

The New England journal of medicine 1964 Mar 19;270;597-603 — 1964 Mar 19 — 597-603

SPAULDING WB

Dangers in the use of some potent drugs.

Canadian Medical Association journal 1962 Dec 15;87;1275-81 — 1962 Dec 15 — 1275-81

ETTER RL, MERRYMAN G

Anaphylactic shock and death due to penicillin; report of a case.

Annals of allergy 1954 Jul-Aug;12;453-4 — 1954 Jul-Aug — 453-4

CURPHEY JT

Fatal anaphylaxis in bronchial asthma following administration of penicillin; report of two cases with autopsy findings.

New York state journal of medicine 1953 May 01;53;1107-10 — 1953 May 01 — 1107-10

Risk of anaphylaxis in a hospital population in relation to the use of various drugs: an international study.

Pharmacoepidemiology and drug safety 2003 Apr-May;12;195-202 — 2003 Apr-May — 195-202

Xi-Moy S, Thorvilson NK, Edmiston CE, Woehlck HJ

Anaphylaxis to penicillin on reperfusion during liver transplantation.

Anesthesiology 2000 Jul;93;280-1 — 2000 Jul — 280-1

Dunn AB, Blomquist J, Khouzami V

Anaphylaxis in labor secondary to prophylaxis against group B Streptococcus. A case report.

The Journal of reproductive medicine 1999 Apr;44;381-4 — 1999 Apr — 381-4

Cullen DJ

Severe anaphylactic reaction to penicillin during halothane anaesthesia. A case report.

British journal of anaesthesia 1971 Apr;43;410-2 — 1971 Apr — 410-2