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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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XII.bt

ST segment elevation

Last update : 01/01/1970
 

Causative drugs

1

CAR T-cell therapy

I.ao I - Interstitial/parenchymal lung disease
I.ao - Pulmonary infiltrates
II.a II - Pulmonary edema - Acute lung injury - ARDS
II.a - Pulmonary edema, noncardiogenic (NCPE)
II.b II - Pulmonary edema - Acute lung injury - ARDS
II.b - ARDS - Acute lung injury
II.r II - Pulmonary edema - Acute lung injury - ARDS
II.r - Interstitial pulmonary edema
III.c III - Pulmonary/alveolar./airway hemorrhage/bleeding
III.c - Hemoptysis
V.a V - Pleural and/or pericardial involvement
V.a - Pleural effusion (uni- or bilateral) (can accompany DI-LDs)
X.an X - Systemic/Distant conditions, syndromes and reactions
X.an - Cytokine release syndrome - Cytokine storm
XII.a XII - Cardiovascular involvement / toxicity
XII.a - Left or biventricular dysfunction/failure
XII.af XII - Cardiovascular involvement / toxicity
XII.af - Coronary vasospasm - Vasospastic angina
XII.ah XII - Cardiovascular involvement / toxicity
XII.ah - Tachycardia
XII.ai XII - Cardiovascular involvement / toxicity
XII.ai - Cardiotoxicity
XII.ba XII - Cardiovascular involvement / toxicity
XII.ba - Sudden cardiac death
XII.bt XII - Cardiovascular involvement / toxicity
XII.bt - ST segment elevation
XVII.b XVII - Infections & related conditions
XVII.b - Opportunistic pulmonary/systemic infections
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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