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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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XXV.a

By proxy: metabolic acidosis

Last update : 01/01/1970
 

Causative drugs

1

Ethylene glycol

XI.d XI - Miscellaneous
XI.d - Metabolic acidosis (incl. lactic acidosis/-gap). May cause hyperpnea/dyspnea
XXV.a XXV - Poisoning by proxy
XXV.a - By proxy: metabolic acidosis
1
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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