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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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XXIV.g

Veterinary: Cardiac arrhythmias

Last update : 01/01/1970
 

Causative drugs

1

Lamotrigine

I.a I - Interstitial/parenchymal lung disease
I.a - Pneumonitis (ILD), acute and/or severe (may cause ARDS)
I.b I - Interstitial/parenchymal lung disease
I.b - Pneumonitis (ILD)
I.d I - Interstitial/parenchymal lung disease
I.d - Organizing pneumonia pattern (an area or areas of consolidation on imaging)
I.m I - Interstitial/parenchymal lung disease
I.m - ILD with a granulomatous component
II.b II - Pulmonary edema - Acute lung injury - ARDS
II.b - ARDS - Acute lung injury
IV.ag IV - Airway involvement
IV.ag - Bronchocentric granulomatosis
X.a X - Systemic/Distant conditions, syndromes and reactions
X.a - DRES syndrome - DRESS-like reaction
X.d X - Systemic/Distant conditions, syndromes and reactions
X.d - Lupus - Lupus syndrome (see also Vd)
X.az X - Systemic/Distant conditions, syndromes and reactions
X.az - Hemophagocytic syndrome
XII.d XII - Cardiovascular involvement / toxicity
XII.d - Myocarditis (can be fulminant)
XII.h XII - Cardiovascular involvement / toxicity
XII.h - Eosinophilic myocarditis
XII.s XII - Cardiovascular involvement / toxicity
XII.s - Heart block (bundle branch- or AV-)
XV.cc XV - Pathology
XV.cc - Path: Eosinophilic myocarditis
XV.cu XV - Pathology
XV.cu - Path: Bronchocentric granulomatosis
XXIV.g XXIV - Veterinary medicine
XXIV.g - Veterinary: Cardiac arrhythmias
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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