Pneumotox » Pattern » IX.h - Dyspnea, unexplained otherwise

IX.h

Dyspnea, unexplained otherwise

Usually , subacute/chronic, lone, with no definite evidence for underlying involvement, disease or explanation. A workup for drug-induced asthma, the 'locked lung', pulmonary embolism, and hemoglobinpathies is required. Ticagrelor is a significant etiologic contributor to this pattern

Last update : 01/01/1970

Causative drugs

26

Ticagrelor

III.a VIII.a IX.e IX.h IX.p IX.u XII.ag

3

1
2

Diagnosing DIRD

1

Drug and radiation history

2

Drug singularity - Correct identification of the drug

3

Consistent timing of exposure v. onset of symptoms

4

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

5

Careful exlusion of another cause

6

Remission of symptoms with removal of drug

7

Recurrence with rechallenge (rarely advisable)

8

Causality assessment

More detailed checklist

The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

IX.h

Dyspnea, unexplained otherwise

Causative drugs

Ticagrelor