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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Irbesartan

3

VIII.a Angioedema (may cause UAO, asphyxia and death)

3
Last update : 02/02/2025
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Angiotensin II receptor blockers (ARB) - Sartans
3
Angiotensin converting enzyme inhibitors (ACEI)
5

Publications

A real-world pharmacovigilance analysis of adverse events associated with irbesartan using the FAERS and JADER databases.
Frontiers in pharmacology 2024;15;1485190 2024
Angiotensin-converting Enzyme Inhibitor Angioedema Requiring Admission to an Intensive Care Unit.
The American journal of medicine 2015 Jul;128;785-9 2015 Jul
Treatment of angiotensin receptor blocker-induced angioedema: A case series.
The Laryngoscope 2015 Jul;125;1619-23 2015 Jul
Side effects of angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists: are we facing a new syndrome.
The American journal of cardiology 2012 Nov 15;110;1552-3 2012 Nov 15

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