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Angiotensin II receptor blockers (ARB) - Sartans

Novel ARB blockers may induce similar class-related adverse events. In some patients, cough or angioedema from ACE inhibitors may also occur with subsequent exposure to ARB. Caution is advised

Last update : 03/10/2018

IV.d Cough (lone)

VIII.a Angioedema (may cause UAO, asphyxia and death)

X.au Visceral angioedema

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

More detailed checklist

The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

Angiotensin II receptor blockers (ARB) - Sartans

IV.d Cough (lone)

VIII.a Angioedema (may cause UAO, asphyxia and death)

X.au Visceral angioedema