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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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E-cigarette - E-vaporizers - ENDS - Vaping - Dabbing

5

XIX.i BAL: Oil red O-stainable material in BAL macrophages othen than exogenous lipids

1

Critical discussion at PMID 31985892

Last update : 28/03/2020
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Abused drugs/substances (illicit-, street drugs - IV/inhaled)
5
Cannabinoids - Cannabinoid receptor agonists (synthetic) (K2, Spice)
5
Diacetyl (2,3-butanedione) flavoring agent
3
E-cigarette's, e-vaporizer's secondhand vapor (Passive vaping)
1
Flavoring agents
5
Glue sniffing
3
Inhalants (volatile substances)
5
Marijuana, cannabis (haschish, hash, bang, dab)
5
Nicotine
1
Nitrous oxide (N2O)
1
Sildenafil
1
Tadalafil
1
Tetrahydrocannabinol (THC)
5
Tobacco smoke - Cigarette smoking
5
Vitamin E acetate (vaped, inhaled)
5

Publications

Bronchoalveolar Lavage (BAL) and Pathologic Assessment of Electronic Cigarette or Vaping Product Use-associated Lung Injury (EVALI): The EVALI-BAL Study, A Multicenter Cohort.
Journal of bronchology & interventional pulmonology 2023 Apr 01;30;144-154 2023 Apr 01
Pulmonary Illness Related to E-Cigarette Use in Illinois and Wisconsin - Final Report.
The New England journal of medicine 2020 Mar 05;382;903-916 2020 Mar 05
Pulmonary Lipid-Laden Macrophages and Vaping.
The New England journal of medicine 2019 Oct 10;381;1488-1489 2019 Oct 10
An unexpected consequence of electronic cigarette use.
Chest 2012 Apr;141;1110-1113 2012 Apr

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