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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Olmesartan

1

VIII.a Angioedema (may cause UAO, asphyxia and death)

1
Last update : 22/11/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Angiotensin II receptor blockers (ARB) - Sartans
3
Angiotensin converting enzyme inhibitors (ACEI)
5

Publications

Treatment of angiotensin receptor blocker-induced angioedema: A case series.
The Laryngoscope 2015 Jul;125;1619-23 2015 Jul
Orolingual angioedema associated with olmesartan use after recombinant tissue plasminogen activator treatment of acute stroke.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2014 Feb;112;177-8 2014 Feb
Side effects of angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists: are we facing a new syndrome.
The American journal of cardiology 2012 Nov 15;110;1552-3 2012 Nov 15
Severe angioedema associated with olmesartan.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2011 Sep;107;285 2011 Sep
Olmesartan medoxomil-induced angioedema.
The Annals of pharmacotherapy 2007 Mar;41;518-20 2007 Mar

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