Pneumotox » Drug » Cyclophosphamide » XVI.bl - Imaging: An area or areas of avid tracer uptake in the lung/chest on 18F-PET scan

Cyclophosphamide

Last update : 23/10/2018

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment