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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Phenobarbital

2

X.a DRES syndrome - DRESS-like reaction

1
Last update : 08/02/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Phenobarbital-induced DRESS: a lichenoïd picture.
Iranian journal of allergy, asthma, and immunology 2014 Dec;13;453-5 2014 Dec
Dress syndrome with sepsis, acute respiratory distress syndrome and pneumomediastinum.
Indian journal of dermatology 2011 Nov;56;763-5 2011 Nov
Eosinophilic myocarditis associated with toxicodermia caused by phenobarbital.
Japanese circulation journal 1998 Feb;62;132-5 1998 Feb

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