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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Cephalosporin(s)

3

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

2
Last update : 13/07/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Antibiotics
5
Beta-lactam antibiotics
5
Cefazolin
1
Cefotiam
1
Cefpodoxime
1
Ceftaroline
1
Ceftriaxone
1

Publications

Adverse reactions associated with oral and parenteral use of cephalosporins: A retrospective population-based analysis.
The Journal of allergy and clinical immunology 2015 Mar;135;745-52.e5 2015 Mar
[Twenty autopsy cases of anaphylactic shock induced by cephalosporins].
Fa yi xue za zhi 2011 Apr;27;125-8 2011 Apr
Perioperative anaphylaxis in a 44-year-old man.
Allergy and asthma proceedings 2007;28;602-5 2007
Anaphylaxis: a review of 601 cases.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2006 Jul;97;39-43 2006 Jul
Drug-induced anaphylaxis : case/non-case study based on an italian pharmacovigilance database.
Drug safety 2005;28;547-56 2005
Cephalosporin allergy.
The New England journal of medicine 2001 Sep 13;345;804-9 2001 Sep 13
[Intraoperative anaphylactic shock--report of two cases].
Ma zui xue za zhi = Anaesthesiologica Sinica 1989 Dec;27;389-93 1989 Dec

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