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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Neuroleptics - Antipsychotics

4

IX.c Chest wall muscle rigidity - Stiff/wooden chest

3
Last update : 13/01/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Chlorpromazine
2
Clozapine
3
Flupentixol
1
Haloperidol
1
Risperidone
1
Zolpidem
1

Publications

Neuroleptic malignant-like syndrome with a slight elevation of creatine-kinase levels and respiratory failure in a patient with Parkinson's disease.
Patient preference and adherence 2014;8;271-3 2014
Neuroleptic malignant syndrome: case report and discussion.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2003 Sep 02;169;439-42 2003 Sep 02

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