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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Transhepatic arterial chemoembolization (TACE)

3

VI.e Fat/oil embolism - The FES embolism syndrome

2
Last update : 03/07/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Doxorubicin - Adriamycin
3
Lipiodol - Iodinated/iodized oil (RCM)
2
Transcatheter embolization
2

Publications

Risk factors for the development of pulmonary oil embolism after transcatheter arterial chemoembolization of hepatic tumors.
Anti-cancer drugs 2014 Sep;25;976-81 2014 Sep
Cerebral iodized lipid embolization via a pulmonary arteriovenous shunt: rare complication of transcatheter arterial embolization for hepatocellular carcinoma.
World journal of surgical oncology 2013 May 30;11;122 2013 May 30
Pulmonary embolism: a fatal complication of arterial chemoembolization for advanced hepatocellular carcinoma.
Journal of pediatric surgery 2005 Oct;40;1647-50 2005 Oct
Hepatic tumors: predisposing factors for complications of transcatheter oily chemoembolization.
Radiology 1996 Jan;198;33-40 1996 Jan
Pulmonary oil embolism after transcatheter oily chemoembolization of hepatocellular carcinoma.
Radiology 1993 Jun;187;689-93 1993 Jun

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