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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Talc (inhaled, sniffed, i.v., intrapleural)

3

XVI.ae Imaging: A pattern similar to pneumoconiotic progressive massive fibrosis (PMF)

2
Last update : 09/01/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Abused drugs/substances (illicit-, street drugs - IV/inhaled)
5
Marijuana, cannabis (haschish, hash, bang, dab)
5

Publications

A man in his early 70s with progressive dyspnea and abnormal fundoscopic examination.
Chest 2014 Jan;145;178-181 2014 Jan
Long-term follow-up of drug abusers with intravenous talcosis.
The American review of respiratory disease 1989 Jan;139;233-41 1989 Jan
Pulmonary 'mainline' granulomatosis: talcosis of intravenous methadone abuse.
Medicine 1979 May;58;229-39 1979 May

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