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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Talc (inhaled, sniffed, i.v., intrapleural)

3

VI.g Foreign body pulmonary vasculopathy (Excipient lung disease)

3
Last update : 08/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Abused drugs/substances (illicit-, street drugs - IV/inhaled)
5
Marijuana, cannabis (haschish, hash, bang, dab)
5

Publications

Imaging of nonthrombotic pulmonary embolism: biological materials, nonbiological materials, and foreign bodies.
European journal of radiology 2013 Mar;82;e120-41 2013 Mar
Diffuse talc granulomatosis in a patient with Crohn's disease.
American journal of respiratory and critical care medicine 2012 Oct 01;186;e11 2012 Oct 01
Pulmonary talc granulomas, pulmonary fibrosis, and pulmonary hypertension resulting from intravenous injection of talc-containing drugs intended for oral use.
Proceedings (Baylor University. Medical Center) 2002 Jul;15;260-1 2002 Jul

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