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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Warfarin

5

V.n Hemopericardium - Bloody pericardial effusion

1
Last update : 05/01/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Abused drugs/substances (illicit-, street drugs - IV/inhaled)
5
Anticoagulants, oral (vitamin K antagonists-VKA)
5
Cocaine
5
Heroin (inhaled, insufflated, snorted)
4
Heroin (intravenous)
5
Superwarfarins (vitamin K super antagonist rodenticides)
4

Publications

Recurrent pericardial effusion caused by pacemaker lead perforation and warfarin therapy at seven years after implantation.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2012 Feb;14;297 2012 Feb
Cardiac tamponade secondary to haemopericardium in a patient on warfarin.
Emergency medicine journal : EMJ 2007 Sep;24;679-80 2007 Sep
Hemopericardium and cardiac tamponade associated with warfarin therapy.
Cleveland Clinic journal of medicine 1993;60;336-8 1993
ANTICOAGULANT-INDUCED HEMOPERICARDIUM WITH TAMPONADE: ITS OCCURRENCE IN THE ABSENCE OF MYOCARDIAL INFARCTION OR PERICARDITIS.
The New England journal of medicine 1965 Apr 01;272;670-4 1965 Apr 01

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