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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Brodifacoum
4
XXIV.d
Veterinary: Pulmonary bleeding (hemoptysis, alveolar hemorrhage)
1
Last update :
09/10/2018
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Anticoagulants, oral (vitamin K antagonists-VKA)
Cannabinoids - Cannabinoid receptor agonists (synthetic) (K2, Spice)
Rodenticides
Superwarfarins (vitamin K super antagonist rodenticides)
Warfarin
Publications
Assessment of toxicity and coagulopathy of brodifacoum in Japanese quail and testing in wild owls.