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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Crack cocaine
5
XV.bj
Path: Alveolar carbonaceous material or deposits
1
Last update :
18/06/2013
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Cocaine
Levamisole
Levamisole-adulterated/tainted cocaine
Publications
The histopathology of drugs of abuse.
Respiratory toxicities from stimulant use.
Little women, Texas, small numbers and coronary artery bypass grafting.
Pulmonary complications from alveolar accumulation of carbonaceous material in a cocaine smoker.