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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Crack cocaine

5

XV.bj Path: Alveolar carbonaceous material or deposits

1
Last update : 18/06/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Cocaine
5
Levamisole
4
Levamisole-adulterated/tainted cocaine
5

Publications

The histopathology of drugs of abuse.
Histopathology 2011 Oct;59;579-93 2011 Oct
Respiratory toxicities from stimulant use.
Clinical reviews in allergy & immunology 1997;15;221-41 1997
Little women, Texas, small numbers and coronary artery bypass grafting.
The American journal of cardiology 1993 Sep 15;72;739-40 1993 Sep 15
Pulmonary complications from alveolar accumulation of carbonaceous material in a cocaine smoker.
Chest 1992 Apr;101;1171-3 1992 Apr

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