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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Levamisole

4

XV.aw Path: Skin vasculopathy/vasculitis/fibrin thrombi

4
Last update : 13/10/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Aminorex
5
Cocaine
5
Crack cocaine
5
Levamisole-adulterated/tainted cocaine
5

Publications

Cocaine and Levamisole Induced Vasculitis.
Cureus 2021 Aug;13;e17192 2021 Aug
p-ANCA-Associated Vasculitis Caused by Levamisole-Adulterated Cocaine: A Case Report.
Case reports in emergency medicine 2013;2013;878903 2013
Levamisole in cocaine: unexpected news from an old acquaintance.
Clinical toxicology (Philadelphia, Pa.) 2012 Apr;50;231-41 2012 Apr
Cocaine induced vasculitis: have we found a culprit?
Case reports in rheumatology 2012;2012;982361 2012
Levamisole-adulterated cocaine: a case series.
Journal of the American Board of Family Medicine : JABFM 2012;25;531-5 2012
Levamisole-induced thrombosis: literature review and pertinent laboratory findings.
Journal of the American Academy of Dermatology 2011 Oct;65;e128-e129 2011 Oct

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