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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Candesartan

1

VIII.a Angioedema (may cause UAO, asphyxia and death)

1
Last update : 11/04/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Angiotensin II receptor blockers (ARB) - Sartans
3

Publications

Treatment of angiotensin receptor blocker-induced angioedema: A case series.
The Laryngoscope 2015 Jul;125;1619-23 2015 Jul
Severe angioedema induced by angiotensin II receptor blocker.
International journal of cardiology 2013 Sep 20;168;e15-6 2013 Sep 20
Angioedema: 6 years experience with fourteen cases.
Auris, nasus, larynx 2010 Apr;37;199-204 2010 Apr
Angioedema, angiotensin converting enzyme inhibitors, and angiotensin receptor blocking drugs.
Canadian journal of anaesthesia = Journal canadien d'anesthesie 2007 Feb;54;155-7; author reply 157 2007 Feb
Angioedema associated with candesartan.
Pharmacotherapy 2002 Sep;22;1176-9 2002 Sep

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