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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Tobacco smoke - Cigarette smoking

5

XV.ay Path: Smoking-related interstitial fibrosis (SRIF). Respiratory bronchiolitis with fibrosis

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Last update : 24/01/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
E-cigarette - E-vaporizers - ENDS - Vaping - Dabbing
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Vaping
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Publications

Smoking-related interstitial fibrosis (SRIF): pathologic findings and distinction from other chronic fibrosing lung diseases.
Journal of clinical pathology 2013 Oct;66;882-7 2013 Oct
Respiratory bronchiolitis with fibrosis. High-resolution computed tomography findings and correlation with pathology.
Annals of the American Thoracic Society 2013 Dec;10;590-601 2013 Dec
Smoking-related interstitial fibrosis (SRIF), pathogenesis and treatment of usual interstitial pneumonia (UIP), and transbronchial biopsy in UIP.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2012 Jan;25 Suppl 1;S68-78 2012 Jan

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