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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Hemotherapy (transfusion/infusion of whole blood, red cells, platelets, or blood products)

5

II.f Hypoxemia, low oxygen saturation (may occur in isolation)

1
Last update : 04/11/2017
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Immunoglobulins, intravenous (IVIG)
3
Lymphocyte (donor) infusion
1
Platelet transfusion
2

Publications

Transfusion-associated hypoxemia in pediatric patients with solid tumors after autologous peripheral blood stem cell transplantation.
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2017 Oct;56;744-747 2017 Oct

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