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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Hemotherapy (transfusion/infusion of whole blood, red cells, platelets, or blood products)

5

XVI.d Imaging: Alveolar opacities or haze with a batwing or butterfly distribution

2
Last update : 21/08/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Immunoglobulins, intravenous (IVIG)
3
Lymphocyte (donor) infusion
1
Platelet transfusion
2

Publications

Transfusion-related acute lung injury: an uncommon cause of pulmonary edema.
Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia 2023 Aug 21;49;e20230175 2023 Aug 21
Radiographic manifestations of transfusion-related acute lung injury.
Clinical imaging 2013;37;1020-3 2013

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