Pneumotox » Drug » Hemotherapy (transfusion/infusion of whole blood, red cells, platelets, or blood products) » II.h - Overload pulmonary edema (including posttransfusional (TACO))

Hemotherapy (transfusion/infusion of whole blood, red cells, platelets, or blood products)

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II.h Overload pulmonary edema (including posttransfusional (TACO))

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Transfusion-associated circulatory overload, a.k.a. TACO

Last update : 30/01/2013

Diagnosing DIRD

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Drug and radiation history

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Drug singularity - Correct identification of the drug

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Consistent timing of exposure v. onset of symptoms

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Clinical, imaging, BAL, pathological pattern consistent with the specific drug

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Careful exlusion of another cause

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Remission of symptoms with removal of drug

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Recurrence with rechallenge (rarely advisable)

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Causality assessment

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