Pneumotox » Drug » Leukotriene receptor antagonists (LTRA) » X.h - Eosinophilic granulomatosis with polyangiitis (Churg-Strauss)

Leukotriene receptor antagonists (LTRA)

3

X.h Eosinophilic granulomatosis with polyangiitis (Churg-Strauss)

3

Although not all authors will agree (PMID 10514017), currently abvailable evidence is consistent with a cause and effect relationship. Drug discontinuation and follow-up upon withdrawal are indicated

Last update : 28/11/2013

Diagnosing DIRD

1

Drug and radiation history

2

Drug singularity - Correct identification of the drug

3

Consistent timing of exposure v. onset of symptoms

4

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

5

Careful exlusion of another cause

6

Remission of symptoms with removal of drug

7

Recurrence with rechallenge (rarely advisable)

8

Causality assessment

More detailed checklist

See also under