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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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XV.co Path: Foamy inclusions in alveolar macrophages and/or in other lung cells

1
Last update : 10/01/2020
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Atorvastatin
1
Ezetimibe
1
Fluvastatin
1
Pitavastatin
1
Pravastatin
2
Rosuvastatin
1
Simvastatin
2

Publications

Statin-induced fibrotic nonspecific interstitial pneumonia.
The European respiratory journal 2002 Mar;19;577-80 2002 Mar

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